Sexual Health Bundle

Some formulas, including Hone’s arousal cream, pack libido-boosting powerhouses like l-arginine and testosterone.

L-arginine is an amino acid often found in pre-workout supplements.

• Viagra cream may be marketed with claims of increased stamina.
• It can be part of a broader sexual wellness routine.
• Some products include herbal or natural extracts.
• Expect varying degrees of success based on individual factors.
• Use in combination with foreplay can enhance results.
• It is not a substitute for medical treatment of ED.
• Some formulations require refrigeration for storage.
• Discontinue if adverse reactions happen promptly.
• The cream should be used responsibly and ethically.
• Do not rely solely on topical products for ED issues.

Like sildenafil, L-arginine promotes better blood flow.

MEET OUR LOW LIBIDO TREATMENT

Rachel Wright, LMFT, is a sex-positive, New York-based licensed psychotherapist. She hosts the podcast “The Wright Conversations” and teaches online workshops. Indeed, it’s often called ‘libido cream’’ because it buy female viagra helps women orgasm more easily. Scream cream isn’t a trademarked name or brand. Various pharmaceutical providers and brands have their own versions of the pleasure-inducing product.

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While formulations differ slightly, they all have the same active ingredient: sildenafil. Sildenafil can enhance blood to various parts of the body, including your genitals (2). Blood flow is crucial for the sexual response cycle, says board-certified pharmacist Nicole Snow, Pharm.D. Increasing blood flow to the vulva promotes natural lubrication, enhances clitoral sensitivity, and intensifies orgasms (3). Libido, generally speaking, describes your interest in sex. It relaxes the smooth muscle in blood vessels, allowing more circulation to areas that matter—like your clitoris (12).

One 2023 study found that blood flow to the clitoris increased within just 5 minutes of using a gel containing L-arginine (13). That means more sensitivity and enhanced arousal—fast. Testosterone is known as the “male” hormone, but it’s critical for women’s sexual health, too, Berkheimer says. Doctors often prescribe it off-label to women to revive a diminished sex drive, Berkheimer explains. Topical testosterone may be especially helpful for women in menopause, Berkheimer adds. One small study on 37 post-menopausal women found liquid viagra that intravaginal testosterone cream significantly improved sexual satisfaction and reduced pain during sex in as little as two weeks. Patience is essential for having a pleasurable experience with topical sildenafil.

As the saying goes, everything comes (ahem) to she who waits. It can take up to 30 minutes for scream cream to absorb into your genital tissues. To get the most out of it, thoroughly massage the cream into your clitoris, labia, and surrounding tissues for 30 to 60 seconds. While you wait for the cream to do its magic, try other activities that support arousal, such as reading or listening to erotica, or snuggling with your partner. And remember, there will be nights when you aren’t in the mood for sex—even after applying the cream—and that’s OK. While scream cream can be a powerful tool in your sexual toolbox, it’s not a wand-waving fairy godmother that makes all of your libido-blocking stressors disappear. If you have a pre-existing health condition, mention it to your doctor when you discuss scream cream, Snow says.

How to Use Scream Cream

If your libido is low, it can affect your mental well-being. It can feel distressing when your desire to have sex unexpectedly vanishes, explains licensed psychotherapist Rachel Wright, LMFT. If your libido has been MIA for months on end, an OB-GYN may diagnose you with female sexual interest/arousal disorder (FSIAD), says psychotherapist and sexologist Joy Berkheimer, Ph.D. (4). FSIAD is marked by a lack of desire for sexual activity and physical arousal, she says (5).

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While FSIAD can impact people at any age, it’s more common in midlife and beyond. “Sexual arousal disorder is seen more frequently in peri- and post-menopause,” Berkheimer says. One 2022 study suggests women ages 51 to 59 are most likely to be affected (6). This age group experiences a rapid decline in estrogen levels, which can negatively affect vaginal lubrication and sexual desire, Berkheimer notes. But there’s a silver lining for those navigating FSIAD: Scream creams and similar products, especially those with testosterone, may help restore your libido. Research shows the drug can increase the risk of severe arrhythmia (abnormal heartbeat) in people with cardiovascular disease (15).

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Although only a handful of studies have explored whether sildenafil creams increase pleasure, they all show promise. One of the first studies on the topic, published in 2020, looked at the effects of topical sildenafil on women ages 25 to 55 who didn’t have sexual dysfunction (7). After watching a 30-minute, sexually explicit film, those who used the cream experienced a significant increase in arousal compared to those who didn’t. That suggests sildenafil may help treat FSIAD, according to the study authors. New studies show scream cream isn’t just about increasing arousal and lubrication.

How it Helps You Do It

One large 2024 study found it can strengthen orgasms after just eight weeks; another from the same year suggests it can reduce anxiety or frustration around sex, too (8, 9). Here’s the catch: So far, studies have only looked at how scream scream can help women before and during perimenopause. This doesn’t mean it won’t help this group, but we need more research to confirm, says Ross. The risks of using scream cream are likely low. Old research suggests oral sildenafil is safe and effective for women in postmenopause (10). You should steer clear of sildenafil if you have a heart condition or recently had a stroke or heart attack, Snow adds.

Treatment Information

The researchers behind a 2024 study also report that sildenafil cream, in general, is safe and well-tolerated by users and their sexual partners (11). “Topical sildenafil products can assist in treating sexual arousal disorder in some women postmenopause,” Ross says. But, “sexual arousal disorder in women is complicated and can have many contributing factors.” Translation: If you’re struggling with low desire, it could be due to stress, relationship dynamics, or body image issues—not just biology. Also, for truly satisfying sex, it’s essential to look at the whole picture. “Relationship counseling, stress reduction, sex therapy, more foreplay, or a weekend away with your partner may all help you get back on track to having good sex—no matter your life stage,” Ross says. Ditto if you have sickle cell anemia, hypotension, or liver issues (16).

DARE to PLAY Sildenafil Cream

The cream is said to work within minutes of being applied to the genital area. According to the Cleveland Clinic, over 40% of women report some degree of sexual dysfunction. “When Viagra was approved in 1998, it revolutionised sexual medicine for men. But for women, comparable progress on enhancing the natural arousal sensations has stalled for nearly three decades,” CEO Sabrina Martucci Johnson said in the release. Prescriptions are currently available for preorder in 10 states, including Connecticut, Florida, Indiana, Missouri, New Hampshire, New Jersey, Oregon, Pennsylvania, Rhode Island and Utah.

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The cream is expected to be available in other states in late 2025 and early 2026. The cream is available as a Section 503B-compounded product, which means it’s manufactured in an outsourcing facility subject to FDA inspection; however, the FDA doesn’t evaluate the treatment for safety, effectiveness or quality. Daré Bioscience is working towards full FDA approval. For far too long, women’s sexual health has been ignored, but that’s starting to change—and it’s about time. Women’s pleasure is taking center stage with libido-boosting “pink pills” and scream cream—a topical that, as the name suggests, can help make you scream in the bedroom. If you have a history of genital herpes, talk to your gynecologist before using scream cream. Research suggests taking high doses of L-arginine can increase the risk of a herpes breakout (17). Any time you start a new prescription drug or skincare product, be on the lookout for adverse effects, especially during your first couple of uses.

Individual Solutions

If you’re going through menopause, hormone replacement therapy (HRT) can address symptoms like vaginal dryness or painful sex that can sabotage your sex life, Ross adds. Products like scream cream also won’t remedy issues like vaginal atrophy, genitourinary syndrome symptoms, and dyspareunia (pain during sex). Only HRT—including vaginal estrogen can help with those, Ross says. In most cases, scream cream can be used in tandem with HRT. Sildenafil is the star ingredient in most scream creams, but many also contain other ingredients that support sexual function. “If you experience side effects such as skin irritation, rash, discomfort, headache, or discoloration after use, discontinue use,” Snow says. If you use a scream cream containing testosterone, keep an eye out for acne, increased body hair, and changes in mood or personality, Berkheimer says. Scream cream and similar products are designed specifically for vulva owners.

Rethinking Sexual Medicine: Inclusion Without Reduction

Scream cream is “the latest addition to the arsenal of medications designed to help women achieve orgasm more easily,” says menopause specialist Sherry Ross, M.D. It can be a godsend for women dealing with common perimenopause and menopause challenges like low libido, vaginal dryness, and difficulty reaching orgasm (1). The good news: These bedroom problems are very treatable. “Products [like scream cream] are thought to increase blood flow to the genitals and erectile tissue of the vulva, which ultimately can increase arousal, pleasure, sensitivity, and orgasm potential,” Ross says. Joy Berkheimer, Ph.D., LMFT, is a psychotherapist and licensed sexologist.

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She is the chief sexologist at SXWA, a sexual wellness award platform. Sherry A. Ross, M.D., FACOG, is a board-certified obstetrics-gynecologist at Providence Saint John’s Health Center in Santa Monica, California. She’s a menopause specialist and the author of She-ology and The She-quel. Nicole Snow, Pharm.D., is a board-certified pharmacist based in Florida and the Clinical Pharmacy Liaison with Olympia Pharmaceuticals. But these products are likely safe for non-op trans men, non-binary folks, and anyone else with a vulva.

But scream cream isn’t made for cisgender men or other penis owners. If you have a penis, are navigating sexual dysfunction, and prefer topical products, talk to your doctor about other options like Eroxon (MED3000)—a recently FDA-approved, over-the-counter gel for erectile dysfunction (18).

• Viagra cream might offer more control over dosing.
• It is often marketed to men seeking non-pill options.
• Some users report increased confidence with topical application.
• The cream is designed for convenience and discreetness.
• It may be combined with lubricants for comfort.
• Skin sensitivity varies, so patch testing is advised.
• The onset of action can be faster than oral forms.
• Interaction with other topical products is unknown.
• Not a cure for sexual dysfunction—only temporary enhancement.
• Consult a healthcare provider about underlying causes of ED.